Hi Simon,
The picture should be fine, 500 pixels vertical is the max, and wide can be larger.
I can't tell how to write a prompt in AI, nor is that the forum to do so. I can provide some tips. But since you use AI, ask what the qualities of Skin appearance are. To create perhaps a communication base with the AI entity. AI will not know the difference in images of retouched toon skin, perhaps, if not defined what qualities you are looking for.
Perhaps find an AI engine that allows you to use reference images, and then mark the area where you would like to have that quality.
Eventually use a subsurface scattering (SSS) material and get the lighting already close to the final, before asking AI to take over.
Test as well the Skin Material of Redshift:
https://help.maxon.net/c4d/2026/en-us/Default.htm#html/COM_REDSHIFT3D_REDSHIFT4C4D_NODES_CORE_SKIN.html
Skin is typically the main challenge as the light goes through several layers. Even small emotions change the blood flow, and tiny changes in color might occur. We are all reading this, more or less conscious.
When it is missing, it often works like with shadows; most people can tell it looks like CG, but what goes wrong is often not clear. Like, often you might notice in CG comps that the light wrap is not even established.
The list of Skin qualities or influences is long and not limited to the ones in the list:
Subsurface Scattering (SSS)
Detailed Texturing (Albedo and Displacement):
Displacement/Normal Maps
Layered Shading Model
Dynamic Changes
Anatomical Accuracy
Lighting
More about light: Think also of the effect of small hairs catching light. Using only "white" light is typically a mistake; bouncing light is typically colorful. Abstract painters have exaggerated this extremely. Cinematographers sometimes use even a color-full bounce board.
Lots of Reference and Observation (Avoid web-based stuff, shoot your own with a gray card)
If nothing helps, add a slightly smaller model (Normal Shift) and create the "under the Skin" results, then blur them a little bit and comp those to a small percentage into the image. (Fake SSS, but only as extra, not replacement of SSS)
All the best